The Reds topped the Brewers 6-1 in the rubber match of a three-game series at Great American Ball Park.
Cincinnati starter Trevor Bauer pitched eight innings of one-run ball and struck out 12 for his fifth victory.
Adrian Houser allowed four runs over four-and-a-third innings to take the loss.
Orlando Arcia drove in Milwaukee’s lone run with a double in the fifth inning.
The 27-and-28 Brewers trail the Cardinals and Reds by one game in the race for second place in the National League Central.
Milwaukee wraps up the regular season with five games at St. Louis beginning tonight (Thursday).
